B3gnt2 Gene Summary [Rat]
Predicted to enable N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity. Predicted to be involved in poly-N-acetyllactosamine biosynthetic process and protein O-linked glycosylation. Predicted to act upstream of or within several processes, including axon guidance; cellular response to leukemia inhibitory factor; and sensory perception of smell. Predicted to be active in Golgi membrane. Orthologous to human B3GNT2 (UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | B3gnt2 |
| Official Name | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 [Source:RGD Symbol;Acc:1310077] |
| Ensembl ID | ENSRNOG00000009267 |
| Bio databases IDs | |
| Aliases | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 |
| Synonyms | 3-Gn-T1, 3-Gn-T2, B3Galt6, B3GNT, B3GNT1, beta-1, BETA3GNT, beta3Gn-T1, Beta 3 Gn-T2, BGnT-1, BGNT2, UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2, UDP-GlcNAc:betaGal β-1,3-N-acetylglucosaminyltransferase 2, β-1, β 3 Gn-T2 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat B3gnt2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase
- UDP-galactose beta-N-acetylglucosamine beta-1,3-galactosyltransferase
- galactosyltransferase
- enzyme
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- migraines
- Huntington disease
role in cell
- proliferation
- N-glycosylation in
- guidance
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Golgi membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat B3gnt2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- protein O-linked glycosylation
- sensory perception of smell
- axon guidance
- keratan sulfate biosynthetic process
- O-glycan processing
- poly-N-acetyllactosamine biosynthetic process
Cellular Component
Where in the cell the gene product is active
- Golgi membrane
Molecular Function
What the gene product does at the molecular level
- protein binding
- UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity
- N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity