Ccdc114 Gene Summary [Rat]
Predicted to be involved in cilium movement and outer dynein arm assembly. Predicted to be located in cilium. Predicted to be part of outer dynein arm and outer dynein arm docking complex. Predicted to be active in axoneme. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia 20. Orthologous to human ODAD1 (outer dynein arm docking complex subunit 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Ccdc114 |
| Official Name | coiled-coil domain containing 114 [Source:RGD Symbol;Acc:1308141] |
| Ensembl ID | ENSRNOG00000021109 |
| Bio databases IDs | |
| Aliases | coiled-coil domain containing 114 |
| Synonyms | CCDC114, CILD20, COILED-COIL DOMAIN-CONTAINING PROTEIN 114: CCDC114, outer dynein arm docking complex subunit 1, RGD1308141 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Ccdc114 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- cilia
- axonemes
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Ccdc114 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- outer dynein arm assembly
- cilium movement
Cellular Component
Where in the cell the gene product is active
- outer dynein arm
- cilium
- axoneme
Molecular Function
What the gene product does at the molecular level
- protein binding