Nlrp9 Gene Summary [Rat]
Predicted to enable ATP binding activity. Predicted to be involved in several processes, including defense response to other organism; positive regulation of interleukin-18 production; and pyroptotic inflammatory response. Predicted to act upstream of or within blastocyst development. Predicted to be part of canonical inflammasome complex. Predicted to be active in cytoplasm. Orthologous to human NLRP9 (NLR family pyrin domain containing 9). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Nlrp9 |
| Official Name | NLR family, pyrin domain containing 9 [Source:RGD Symbol;Acc:1308981] |
| Ensembl ID | ENSRNOG00000021913 |
| Bio databases IDs | |
| Aliases | NLR family, pyrin domain containing 9 |
| Synonyms | CLR19.1, NALP9, Nalp9a, Nalp9b, NLR family pyrin domain containing 9, NLR family, pyrin domain containing 9, Nlrp9b, NOD6, PAN12 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Nlrp9 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- NLRC4 helical domain HD2
- PAAD/DAPIN/Pyrin domain
- NOD2 winged helix domain
- protein phosphatase 1 regulatory subunit 42
- Leucine rich repeat, ribonuclease inhibitor type
- protein binding
- NACHT domain
- Death Domain Superfamily of protein-protein interaction domains
- P-loop containing Nucleoside Triphosphate Hydrolases
- AAA domain
Pathways
Biological processes and signaling networks where the Nlrp9 gene in rat plays a role, providing insight into its function and relevance in health or disease.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Nlrp9 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- inflammatory response
- innate immune response
- pyroptosis
- defense response to virus
- regulation of inflammatory response
- positive regulation of interleukin-18 production
Cellular Component
Where in the cell the gene product is active
- cytoplasm
Molecular Function
What the gene product does at the molecular level
- ATP binding
- protein binding