Mtmr12 Gene Summary [Rat]
Predicted to enable phosphatidylinositol-3-phosphate phosphatase activity. Predicted to be involved in phosphatidylinositol dephosphorylation. Predicted to be located in sarcomere and sarcoplasmic reticulum. Predicted to be active in cytoplasm and membrane. Orthologous to human MTMR12 (myotubularin related protein 12). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Mtmr12 |
| Official Name | myotubularin related protein 12 [Source:RGD Symbol;Acc:1307902] |
| Ensembl ID | ENSRNOG00000022929 |
| Bio databases IDs | |
| Aliases | myotubularin related protein 12 |
| Synonyms | 3-PAP, 4932703C11, C730015A02Rik, mKIAA1682, myotubularin related protein 12, PIP3AP |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Mtmr12 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Myotubularin-associated protein
- Myotubularin-like phosphatase domain
- protein binding
- Pleckstrin homology-like domain
- PTP_DSP_cys
- SET-interacting domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- Cytoplasm
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Mtmr12 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- phosphatidylinositol dephosphorylation
Cellular Component
Where in the cell the gene product is active
- sarcoplasmic reticulum
- cytoplasm
- cytosol
- sarcomere
Molecular Function
What the gene product does at the molecular level
- protein binding