Ggn Gene Summary [Rat]

Predicted to enable identical protein binding activity and ubiquitin protein ligase binding activity. Predicted to be involved in gamete generation. Predicted to act upstream of or within double-strand break repair; embryo implantation; and protein localization. Predicted to be located in perinuclear region of cytoplasm. Human ortholog(s) of this gene implicated in spermatogenic failure 69. Orthologous to human GGN (gametogenetin). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Ggn
Official Name
gametogenetin [Source:RGD Symbol;Acc:1306765]
Ensembl ID
ENSRNOG00000023931
Bio databases IDs NCBI: 292765 Ensembl: ENSRNOG00000023931
Aliases gametogenetin
Synonyms AI593290, gametogenetin
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Ggn often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • ubiquitin protein ligase binding
  • protein binding
  • nucleolar targeting motif
  • identical protein binding
  • Gametogenetin

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • spermatogenic failure 69
  • prostate cancer
regulates
role in cell
  • double-stranded DNA break repair in
  • downregulation in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • Cytoplasm
  • perinuclear region
  • nucleoli
  • nuclear envelope

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Ggn gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • spermatogenesis
  • cell differentiation
  • gamete generation
  • double-strand break repair

Molecular Function

What the gene product does at the molecular level
  • ubiquitin protein ligase binding
  • protein binding

Gene-Specific Assays for Results You Can Trust

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