Nipal1 Gene Summary [Rat]

Predicted to enable magnesium ion transmembrane transporter activity. Predicted to be involved in magnesium ion transport. Predicted to be located in Golgi apparatus. Predicted to be active in membrane. Orthologous to human NIPAL1 (NIPA like domain containing 1). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Nipal1
Official Name
NIPA-like domain containing 1 [Source:RGD Symbol;Acc:1310092]
Ensembl ID
ENSRNOG00000025882
Bio databases IDs NCBI: 289594 Ensembl: ENSRNOG00000025882
Aliases NIPA-like domain containing 1
Synonyms 3830408G10Rik, NIPA3, NIPA-like domain containing 1, NPAL1, RGD1310092, SLC57A3
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Nipal1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • EamA-like transporter family
  • Magnesium transporter NIPA

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • gout
  • uterine leiomyoma
  • leiomyomatosis
  • spinal osteoarthritis
  • opioid dependence
regulated by
regulates
  • insulin
  • INSR
  • magnesium

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Golgi Apparatus

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Nipal1 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • magnesium ion transport

Cellular Component

Where in the cell the gene product is active
  • membrane
  • Golgi membrane
  • Golgi apparatus

Molecular Function

What the gene product does at the molecular level
  • magnesium ion transmembrane transporter activity

Gene-Specific Assays for Results You Can Trust

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