Nipal1 Gene Summary [Mouse]
Predicted to enable magnesium ion transmembrane transporter activity. Involved in magnesium ion transport. Located in Golgi apparatus. Is expressed in cerebral cortex ventricular layer. Orthologous to human NIPAL1 (NIPA like domain containing 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Nipal1 |
| Official Name | NIPA-like domain containing 1 [Source:MGI Symbol;Acc:MGI:1917951] |
| Ensembl ID | ENSMUSG00000067219 |
| Bio databases IDs | |
| Aliases | NIPA-like domain containing 1 |
| Synonyms | 3830408G10Rik, NIPA3, NIPA-like domain containing 1, NPAL1, RGD1310092, SLC57A3 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Nipal1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- EamA-like transporter family
- Magnesium transporter NIPA
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Golgi Apparatus
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Nipal1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- magnesium ion transport
Cellular Component
Where in the cell the gene product is active
- membrane
- Golgi membrane
- Golgi apparatus
Molecular Function
What the gene product does at the molecular level
- magnesium ion transmembrane transporter activity