Ip6k3 Gene Summary [Rat]
Predicted to enable inositol hexakisphosphate 6-kinase activity. Predicted to be involved in inositol phosphate biosynthetic process; phosphatidylinositol phosphate biosynthetic process; and protein phosphorylation. Predicted to act upstream of or within locomotion. Predicted to be active in cytoplasm and nucleus. Orthologous to human IP6K3 (inositol hexakisphosphate kinase 3). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Ip6k3 |
| Official Name | inositol hexakisphosphate kinase 3 [Source:RGD Symbol;Acc:1584104] |
| Ensembl ID | ENSRNOG00000025883 |
| Bio databases IDs | |
| Aliases | inositol hexakisphosphate kinase 3 |
| Synonyms | D830007E07Rik, IHPK3, inositol hexakisphosphate kinase 3, inositol hexaphosphate kinase 3, INSP6K3, LOC100363900 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Ip6k3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- kinase
- diphosphoinositol-pentakisphosphate kinase
- phosphate group acceptor phosphotransferase
- inositol-hexakisphosphate kinase
- alcohol group acceptor phosphotransferase
- Inositol polyphosphate kinase
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- pain
- multiple sclerosis
- schizophrenia
- insomnia
- hypothyroidism
- diabetic nephropathy
- otosclerosis
- gait disturbance
role in cell
- phosphorylation in
- quantity
- survival
- formation
- abnormal morphology
- density
- structural alteration
- volume
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Nucleus
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Ip6k3 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- inositol phosphate metabolic process
- inositol phosphate biosynthetic process
- locomotion
- phosphatidylinositol phosphorylation
- phosphatidylinositol metabolic process
- protein phosphorylation
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytoplasm
- cytosol
Molecular Function
What the gene product does at the molecular level
- ATP binding
- inositol heptakisphosphate kinase activity
- protein binding
- inositol hexakisphosphate kinase activity
- inositol-1,3,4,5,6-pentakisphosphate kinase activity
- inositol diphosphate tetrakisphosphate kinase activity
- inositol hexakisphosphate 5-kinase activity
- inositol 5-diphosphate pentakisphosphate 5-kinase activity
- inositol hexakisphosphate 6-kinase activity
- inositol hexakisphosphate 3-kinase activity
- inositol hexakisphosphate 1-kinase activity