Uqcc2 Gene Summary [Rat]
Predicted to be involved in several processes, including mitochondrial respiratory chain complex III assembly; positive regulation of mitochondrial translation; and regulation of insulin secretion. Predicted to be located in mitochondrion and nuclear body. Predicted to be active in mitochondrial matrix. Human ortholog(s) of this gene implicated in mitochondrial complex III deficiency nuclear type 7. Orthologous to human UQCC2 (ubiquinol-cytochrome c reductase complex assembly factor 2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Nonsense Mediated Decay |
| Official Symbol | Uqcc2 |
| Official Name | ubiquinol-cytochrome c reductase complex assembly factor 2 [Source:RGD Symbol;Acc:1306917] |
| Ensembl ID | ENSRNOG00000025909 |
| Bio databases IDs | |
| Aliases | ubiquinol-cytochrome c reductase complex assembly factor 2 |
| Synonyms | 2900010M23Rik, bA6B20.2, C6orf125, C6orf126, Cbp6, LOC687308, M19, MC3DN7, MNF1, RGD1306917, ubiquinol-cytochrome c reductase complex assembly factor 2 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Uqcc2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Complex III assembly factor UQCC2/CBP6
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Mitochondria
- mitochondrial matrix
- mitochondrial nucleoids
- mitochondrial intermembrane space
- mitochondrial inner membrane
- nuclear bodies
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Uqcc2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- regulation of insulin secretion
- mitochondrial respiratory chain complex III assembly
- regulation of oxidative phosphorylation
- positive regulation of mitochondrial translation
- regulation of skeletal muscle cell differentiation
Cellular Component
Where in the cell the gene product is active
- mitochondrial intermembrane space
- nuclear body
- mitochondrial matrix
- mitochondrion
- mitochondrial inner membrane
- mitochondrial nucleoid
Molecular Function
What the gene product does at the molecular level
- protein binding