Uqcc3 Gene Summary [Rat]
Complex III is a mitochondrial inner membrane protein complex that transfers electrons from ubiquinol to cytochrome c. This gene encodes a protein that functions in complex III assembly. Mutations in this gene result in Mitochondrial complex III deficiency, nuclear type 9. [provided by RefSeq, Dec 2014]
Details
| Type | Protein Coding |
| Official Symbol | Uqcc3 |
| Official Name | ubiquinol-cytochrome c reductase complex assembly factor 3 [Source:RGD Symbol;Acc:1597344] |
| Ensembl ID | ENSRNOG00000045561 |
| Bio databases IDs | |
| Aliases | ubiquinol-cytochrome c reductase complex assembly factor 3 |
| Synonyms | AI462493, C11orf83, Cbp4, CCDS41658.1, MC3DN9, ubiquinol-cytochrome c reductase complex assembly factor 3, UNQ655 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Uqcc3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- phospholipid binding
- binding protein
- CBP4
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- neoplasia
- organismal death
- nuclear type 9 mitochondrial complex III deficiency
regulated by
- ARID1A
- 10-(6'-ubiquinonyl)decyltriphenylphosphonium
- bexarotene
role in cell
- production in
- expression in
- proliferation
- formation
- generation in
- accumulation in
- assembly in
- structure
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- Mitochondria
- cytosol
- mitochondrial inner membrane
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Uqcc3 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cristae formation
- mitochondrial respiratory chain complex III assembly
- mitochondrial electron transport, ubiquinol to cytochrome c
- ATP biosynthetic process
Cellular Component
Where in the cell the gene product is active
- mitochondrion
- cytosol
- mitochondrial respiratory chain complex III
- mitochondrial inner membrane
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- phosphatidic acid binding