Acad9 Gene Summary [Rat]

Predicted to enable long-chain fatty acyl-CoA dehydrogenase activity and medium-chain fatty acyl-CoA dehydrogenase activity. Predicted to be involved in long-chain fatty acid metabolic process; medium-chain fatty acid metabolic process; and mitochondrial respiratory chain complex I assembly. Predicted to be located in dendrite; mitochondrial membrane; and nucleus. Human ortholog(s) of this gene implicated in nuclear type mitochondrial complex I deficiency 20. Orthologous to human ACAD9 (acyl-CoA dehydrogenase family member 9). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Acad9
Official Name
acyl-CoA dehydrogenase family, member 9 [Source:RGD Symbol;Acc:727973]
Ensembl ID
ENSRNOG00000014178
Bio databases IDs NCBI: 294973 Ensembl: ENSRNOG00000014178
Aliases acyl-CoA dehydrogenase family, member 9
Synonyms 2600017P15RIK, 4732402K02, acyl-CoA dehydrogenase family member 9, acyl-CoA dehydrogenase family, member 9, acyl-Coenzyme A dehydrogenase family, member 9, C630012L17RIK, MC1DN20, NPD002, NYGGF2
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Acad9 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Acyl-CoA dehydrogenase, C-terminal domain
  • acyl-CoA dehydrogenase
  • Acyl-CoA dehydrogenase, middle domain
  • enzyme
  • protein binding
  • long-chain-acyl-CoA dehydrogenase
  • Acyl-CoA dehydrogenase, N-terminal domain

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • ACAD9 deficiency
  • Mitochondrial complex I deficiency
  • insulin resistance
regulated by
regulates
  • Mitochondrial ETC 1
  • long chain fatty acid

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Nucleus
  • Mitochondria
  • mitochondrial membrane
  • mitochondrial inner membrane
  • dendrites

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Acad9 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • long-chain fatty acid metabolic process
  • medium-chain fatty acid metabolic process
  • mitochondrial respiratory chain complex I assembly

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • dendrite
  • mitochondrial membrane
  • mitochondrion
  • mitochondrial inner membrane

Molecular Function

What the gene product does at the molecular level
  • acyl-CoA dehydrogenase activity
  • protein binding
  • medium-chain-acyl-CoA dehydrogenase activity
  • flavin adenine dinucleotide binding
  • long-chain-acyl-CoA dehydrogenase activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.