Mri1 Gene Summary [Rat]
Predicted to enable S-methyl-5-thioribose-1-phosphate isomerase activity and identical protein binding activity. Predicted to be involved in L-methionine salvage from methylthioadenosine. Predicted to be located in cytosol; fibrillar center; and nucleoplasm. Orthologous to human MRI1 (methylthioribose-1-phosphate isomerase 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Mri1 |
| Official Name | methylthioribose-1-phosphate isomerase 1 [Source:RGD Symbol;Acc:1307789] |
| Ensembl ID | ENSRNOG00000026211 |
| Bio databases IDs | |
| Aliases | methylthioribose-1-phosphate isomerase 1 |
| Synonyms | 2410018C20Rik, M1Pi, methylthioribose-1-phosphate isomerase 1, MRDI, MTNA, RGD1307789, Ypr118w |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Mri1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- 5-methylthioribose-1-phosphate isomerase
- ribose 1,5-bisphosphate isomerase
- Initiation factor 2 subunit family
- protein binding
- identical protein binding
- translation regulator
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- fibrillar center
- cytosol
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Mri1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- L-methionine biosynthetic process from S-adenosylmethionine
- L-methionine salvage from methylthioadenosine
Cellular Component
Where in the cell the gene product is active
- cytosol
- cell projection
- fibrillar center
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- identical protein binding
- protein binding
- S-methyl-5-thioribose-1-phosphate isomerase activity