NEWGENE_1310139 Gene Summary [Rat]
Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in cytoskeleton organization and intracellular signal transduction. Predicted to be located in cytoplasm. Orthologous to human MAST4 (microtubule associated serine/threonine kinase family member 4). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | NEWGENE_1310139 |
| Official Name | microtubule associated serine/threonine kinase family member 4 [Source:RGD Symbol;Acc:9344213] |
| Ensembl ID | ENSRNOG00000027002 |
| Bio databases IDs | |
| Aliases | microtubule associated serine/threonine kinase family member 4 |
| Synonyms | 4930420O11Rik, microtubule associated serine/threonine kinase family member 4, mKIAA0303, RGD1310139 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Newgene_1310139 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- kinase
- Serine/Threonine protein kinases, catalytic domain
- Domain present in PSD-95, Dlg, and ZO-1/2
- protein serine/threonine kinase
- Protein kinase (unclassified specificity)
- Protein Kinases, catalytic domain
- Protein tyrosine and serine/threonine kinase
- canonical PDZ domain
- Protein kinase domain
- PDZ domain
- Domain of unknown function (DUF1908)
- Tyrosine kinase, catalytic domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- COVID-19
- epithelial cancer
- prostate cancer
- breast cancer
- coronary artery disease
- metabolic syndrome X
- colorectal cancer
- chronic lymphocytic leukemia
- bullous pemphigoid
- non-insulin-dependent diabetes mellitus
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Newgene_1310139 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cytoskeleton organization
- peptidyl-serine phosphorylation
- intracellular signal transduction
Cellular Component
Where in the cell the gene product is active
- cytoplasm
Molecular Function
What the gene product does at the molecular level
- magnesium ion binding
- ATP binding
- protein serine/threonine kinase activity