Akap17a Gene Summary [Rat]

Predicted to enable protein kinase A binding activity. Predicted to be involved in regulation of RNA splicing. Predicted to be located in nucleus. Predicted to be active in cytosol and nuclear speck. Orthologous to human AKAP17A (A-kinase anchoring protein 17A). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Akap17a
Official Name
A-kinase anchoring protein 17A [Source:RGD Symbol;Acc:1564640]
Ensembl ID
ENSRNOG00000028211
Bio databases IDs NCBI: 288526 Ensembl: ENSRNOG00000028211
Aliases A-kinase anchoring protein 17A
Synonyms 721P, A-kinase anchoring protein 17A, CCDC133, CXYorf3, DXYS155E, PRKA17A, SFRS17A, XE7, XE7Y
Species
Rat, Rattus norvegicus
OrthologiesHuman

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Akap17a often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • flagellar export protein FliJ
  • RNA recognition motif (RRM) superfamily
  • Arginine and glutamate-rich 1
  • protein kinase A binding
  • MAP7 (E-MAP-115) family
  • Ezrin/radixin/moesin, alpha-helical domain
  • RNA recognition motif
  • protein binding

Pathways

Biological processes and signaling networks where the Akap17a gene in rat plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • Klinefelter syndrome
  • Turner syndrome
regulated by
  • DAP3
  • MIR3648
  • camptothecin
  • B lymphocytes

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • cellular membrane
  • cytosol
  • nuclear speckles

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Akap17a gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • RNA splicing
  • signal transduction
  • regulation of RNA splicing
  • regulation of transcription, DNA-dependent
  • mRNA processing
  • B cell activation

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • nuclear speck
  • cytosol
  • spliceosomal complex

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • RNA binding
  • protein kinase A binding

Gene-Specific Assays for Results You Can Trust

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