Gbp4

Predicted to enable GTP binding activity; GTPase activity; and protein homodimerization activity. Predicted to be involved in several processes, including cellular response to lipopolysaccharide; defense response to other organism; and positive regulation of defense response. Predicted to act upstream of or within adhesion of symbiont to host and cellular response to interferon-beta. Predicted to be located in several cellular components, including Golgi apparatus; cytosol; and perinuclear region of cytoplasm. Predicted to be active in cytoplasmic vesicle. Orthologous to human GBP4 (guanylate binding protein 4). [provided by Alliance of Genome Resources, Apr 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Gbp4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.