Wdr44 Gene Summary [Rat]
Enables small GTPase binding activity. Involved in regulation of cell migration. Located in microtubule and perinuclear region of cytoplasm. Orthologous to human WDR44 (WD repeat domain 44). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Wdr44 |
| Official Name | WD repeat domain 44 [Source:RGD Symbol;Acc:727965] |
| Ensembl ID | ENSRNOG00000029068 |
| Bio databases IDs | |
| Aliases | WD repeat domain 44 |
| Synonyms | 2610034K17Rik, RAB11BP, RPH11, SYM-4, WD repeat domain 44 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Wdr44 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- WD40 repeats
- WD domain, G-beta repeat
- enzyme binding
- WD40
- protein binding
- Serine Proline motif
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- perinuclear region
- Golgi Apparatus
- microtubules
- endosomal membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Wdr44 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- regulation of vesicle-mediated transport
Cellular Component
Where in the cell the gene product is active
- perinuclear region of cytoplasm
- cytosol
- endosome membrane
- Golgi apparatus
Molecular Function
What the gene product does at the molecular level
- protein binding
- small GTPase binding