Pigx Gene Summary [Rat]
This gene encodes a type I transmembrane protein in the endoplasmic reticulum (ER). The protein is an essential component of glycosylphosphatidylinositol-mannosyltransferase I, which transfers the first of the four mannoses in the GPI-anchor precursors during GPI-anchor biosynthesis. The protein is translated from a non-AUG translation initiation site. [provided by RefSeq, Jul 2008]
Details
| Type | Protein Coding |
| Official Symbol | Pigx |
| Official Name | phosphatidylinositol glycan anchor biosynthesis, class X [Source:RGD Symbol;Acc:1307289] |
| Ensembl ID | ENSRNOG00000033623 |
| Bio databases IDs | |
| Aliases | phosphatidylinositol glycan anchor biosynthesis, class X |
| Synonyms | 2010319C14Rik, phosphatidylinositol glycan anchor biosynthesis class X, phosphatidylinositol glycan anchor biosynthesis, class X, RGD1307289 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Pigx often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- PIG-X / PBN1
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- endoplasmic reticulum membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Pigx gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- GPI anchor biosynthetic process
Cellular Component
Where in the cell the gene product is active
- endoplasmic reticulum membrane