Cfap52

Predicted to be involved in establishment of left/right asymmetry and flagellated sperm motility. Predicted to act upstream of or within several processes, including microtubule sliding; single fertilization; and spermatid development. Predicted to be located in 9+2 motile cilium and axonemal microtubule. Predicted to be active in axonemal B tubule inner sheath and sperm midpiece. Human ortholog(s) of this gene implicated in visceral heterotaxy 10. Orthologous to human CFAP52 (cilia and flagella associated protein 52). [provided by Alliance of Genome Resources, Jul 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Cfap52 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

Biological processes and signaling networks where the Cfap52 gene in rat plays a role, providing insight into its function and relevance in health or disease.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the rat Cfap52 gene, providing context for its role in the cell.