Elmod3 Gene Summary [Rat]

Predicted to act upstream of or within several processes, including cilium assembly; inner ear receptor cell development; and sensory perception of sound. Predicted to be located in cytoskeleton; kinocilium; and stereocilium. Predicted to be active in Golgi apparatus and cilium. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 81 and autosomal recessive nonsyndromic deafness 88. Orthologous to human ELMOD3 (ELMO domain containing 3). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Elmod3
Official Name
ELMO domain containing 3 [Source:RGD Symbol;Acc:1306408]
Ensembl ID
ENSRNOG00000038102
Bio databases IDs NCBI: 297342 Ensembl: ENSRNOG00000038102
Aliases ELMO domain containing 3
Synonyms C330008I15Rik, DFNA81, DFNB88, ELMO/CED-12 domain containing 3, ELMO domain containing 3, Kcmf1, LST3, RBED1, RBM29
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Elmod3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • ELMO/CED-12 family
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
disease
  • familial nonsyndromic hearing impairment
  • autosomal dominant deafness type 81
  • autosomal recessive deafness type 88
regulated by
role in cell
  • organization
  • maintenance

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • cilia
  • Golgi Apparatus
  • cytosol
  • synaptosomes

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Elmod3 gene, providing context for its role in the cell.

Cellular Component

Where in the cell the gene product is active
  • cytoskeleton
  • cytoplasm
  • kinocilium
  • stereocilium

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • GTPase activator activity

Gene-Specific Assays for Results You Can Trust

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