Ak6 Gene Summary [Rat]
Predicted to enable several functions, including ATPase binding activity; C2H2 zinc finger domain binding activity; and p53 binding activity. Predicted to contribute to RNA polymerase II general transcription initiation factor activity and histone acetyltransferase activity. Involved in positive regulation of transcription by RNA polymerase II and response to L-glutamate. Predicted to be located in nucleoplasm. Predicted to be part of SAGA complex; nucleoplasm; and pre-snoRNP complex. Orthologous to human TAF9 (TATA-box binding protein associated factor 9). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Ak6 |
| Official Name | adenylate kinase 6 [Source:RGD Symbol;Acc:7387335] |
| Ensembl ID | ENSRNOG00000039848 |
| Bio databases IDs | |
| Aliases | adenylate kinase 6 |
| Synonyms | 2810046E22Rik, 4921516M08Rik, AD-004, adenylate kinase 6, AK/ATPase, CGI-137, CINAP, CIP, hCINAP |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Ak6 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- kinase
- shikimate kinase
- nucleoside-phosphate kinase
- adenylate kinase
- NK
- UMP-CMP kinase family
- N-terminal helicase domain of the DEAD-box helicase superfamily
- protein binding
- P-loop containing Nucleoside Triphosphate Hydrolases
- AAA domain
Pathways
Biological processes and signaling networks where the Ak6 gene in rat plays a role, providing insight into its function and relevance in health or disease.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- centrosome
- nucleoplasm
- nuclear speckles
- Cajal bodies
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Ak6 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- nucleobase-containing small molecule interconversion
- ribosomal small subunit biogenesis
- nucleoside monophosphate phosphorylation
- rRNA processing
Cellular Component
Where in the cell the gene product is active
- nucleus
- centrosome
- cytoplasm
- nuclear speck
- membrane
- Cajal body
- nucleolus
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- nucleoside phosphate kinase activity
- ATPase activity
- ATP binding
- adenylate kinase activity
- protein binding