Tlr12 Gene Summary [Rat]
Predicted to enable signaling receptor activity. Predicted to be involved in inflammatory response and toll-like receptor signaling pathway. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Tlr12 |
| Official Name | toll-like receptor 12 [Source:RGD Symbol;Acc:1559145] |
| Ensembl ID | ENSRNOG00000042455 |
| Bio databases IDs | |
| Aliases | toll-like receptor 12 |
| Synonyms | Gm1365, RGD1559145, Tlr11, toll-like receptor 12 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Tlr12 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein phosphatase 1 regulatory subunit 42
- SEFIR domain
- Leucine rich repeat
- Leucine Rich repeats (2 copies)
Pathways
Biological processes and signaling networks where the Tlr12 gene in rat plays a role, providing insight into its function and relevance in health or disease.
- Altered T Cell and B Cell Signaling in Rheumatoid Arthritis
- Colorectal Cancer Metastasis Signaling
- Communication between Innate and Adaptive Immune Cells
- Neuroinflammation Signaling Pathway
- Parkinson's Signaling Pathway
- Phagosome Formation
- Role of Macrophages, Fibroblasts and Endothelial Cells in Rheumatoid Arthritis
- TREM1 Signaling
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- cellular membrane