Kyat3 Gene Summary [Rat]
Predicted to enable kynurenine-glyoxylate transaminase activity; kynurenine-oxoglutarate transaminase activity; and protein homodimerization activity. Predicted to be involved in 2-oxoglutarate metabolic process and kynurenine metabolic process. Predicted to be active in mitochondrion. Orthologous to human KYAT3 (kynurenine aminotransferase 3). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Kyat3 |
| Official Name | kynurenine aminotransferase 3 [Source:RGD Symbol;Acc:1359262] |
| Ensembl ID | ENSRNOG00000043426 |
| Bio databases IDs | |
| Aliases | kynurenine aminotransferase 3 |
| Synonyms | CCBL2, KAT3, KATIII, kynurenine aminotransferase 3, LOC100361841 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Kyat3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- tyrosine/nicotianamine family aminotransferase
- tyrosine aminotransferase, eukaryotic
- kynurenine-oxoglutarate transaminase
- putative C-S lyase
- protein homodimerization
- AAT_I
- enzyme
- Aminotransferase class I and II
- kynurenine-glyoxylate transaminase
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Mitochondria
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Kyat3 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- kynurenine metabolic process
- cellular amino acid metabolic process
- biosynthetic process
- 2-oxoglutarate metabolic process
- L-kynurenine catabolic process
Cellular Component
Where in the cell the gene product is active
- cytoplasm
- mitochondrion
Molecular Function
What the gene product does at the molecular level
- pyridoxal phosphate binding
- protein homodimerization activity
- RNA binding
- kynurenine-glyoxylate transaminase activity
- cysteine-S-conjugate beta-lyase activity
- kynurenine-oxoglutarate transaminase activity