Gatd1 Gene Summary [Rat]

Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
Gatd1
Official Name
glutamine amidotransferase like class 1 domain containing 1 [Source:RGD Symbol;Acc:1304836]
Ensembl ID
ENSRNOG00000046382
Bio databases IDs NCBI: 100911365 NCBI: 309110 Ensembl: ENSRNOG00000046382
Aliases glutamine amidotransferase like class 1 domain containing 1
Synonyms D230016J19Rik, FERRY5, Fy-5, glutamine amidotransferase class 1 domain containing 1, glutamine amidotransferase like class 1 domain containing 1, LOC100911365, PDDC1, RGD1304836
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Gatd1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Type 1 glutamine amidotransferase (GATase1)-like domain

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • Fuchs endothelial dystrophy
regulated by
  • myoblasts
  • PMID 35110406 compound 9

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Gatd1 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • methylglyoxal catabolic process to D-lactate
  • lactate biosynthetic process

Cellular Component

Where in the cell the gene product is active
  • early endosome
  • extracellular vesicular exosome
  • cytoplasm

Molecular Function

What the gene product does at the molecular level
  • glyoxalase III activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.