Gatd1 Gene Summary [Mouse]
Predicted to enable glyoxalase III activity. Predicted to be involved in methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione. Predicted to be located in early endosome and extracellular region. Predicted to be active in cytoplasm. Orthologous to human GATD1 (glutamine amidotransferase class 1 domain containing 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Gatd1 |
| Official Name | glutamine amidotransferase like class 1 domain containing 1 [Source:MGI Symbol;Acc:MGI:2387178] |
| Ensembl ID | ENSMUSG00000051007 |
| Bio databases IDs | |
| Aliases | glutamine amidotransferase like class 1 domain containing 1 |
| Synonyms | D230016J19Rik, FERRY5, Fy-5, glutamine amidotransferase class 1 domain containing 1, glutamine amidotransferase like class 1 domain containing 1, LOC100911365, PDDC1, RGD1304836 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Gatd1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Type 1 glutamine amidotransferase (GATase1)-like domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Gatd1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- methylglyoxal catabolic process to D-lactate
- lactate biosynthetic process
Cellular Component
Where in the cell the gene product is active
- early endosome
- extracellular vesicular exosome
- cytoplasm
Molecular Function
What the gene product does at the molecular level
- glyoxalase III activity