Nemp1 Gene Summary [Rat]

Predicted to be involved in erythrocyte enucleation and nuclear membrane organization. Predicted to be located in nuclear inner membrane. Predicted to be active in nuclear envelope. Orthologous to human NEMP1 (nuclear envelope integral membrane protein 1). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Nemp1
Official Name
nuclear envelope integral membrane protein 1 [Source:RGD Symbol;Acc:1587179]
Ensembl ID
ENSRNOG00000046492
Bio databases IDs NCBI: 679504 Ensembl: ENSRNOG00000046492
Aliases nuclear envelope integral membrane protein 1
Synonyms nuclear envelope integral membrane protein 1, Q8k2n3, TMEM194, TMEM194A
Species
Rat, Rattus norvegicus
OrthologiesHuman

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Nemp1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • NEMP family
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • anemia
  • headache
  • acute myeloid leukemia
  • insomnia
regulated by
role in cell
  • organization
  • maturation
  • enucleation

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • cellular membrane
  • nuclear envelope

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Nemp1 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • enucleation
  • nuclear membrane organization
  • erythrocyte maturation

Cellular Component

Where in the cell the gene product is active
  • nuclear envelope
  • nuclear inner membrane

Gene-Specific Assays for Results You Can Trust

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