Tspan33 Gene Summary [Rat]
Predicted to enable enzyme binding activity. Predicted to be involved in pore complex assembly; protein localization to plasma membrane; and protein maturation. Predicted to be located in cell surface and tetraspanin-enriched microdomain. Predicted to be part of pore complex. Predicted to be active in plasma membrane. Orthologous to human TSPAN33 (tetraspanin 33). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Tspan33 |
| Official Name | tetraspanin 33 [Source:RGD Symbol;Acc:1560915] |
| Ensembl ID | ENSRNOG00000007900 |
| Bio databases IDs | |
| Aliases | tetraspanin 33 |
| Synonyms | 1300010A20Rik, PEN, PEN., RGD1560915, tetraspanin 33 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Tspan33 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- tetraspanin_LEL
- enzyme binding
- protein binding
- Tetraspanin family
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- major depression
- neoplasia
- anemia
- splenomegaly
- opioid dependence
- thrombocytopenia
- leptocytosis
- macrocytosis
role in cell
- expression in
- quantity
- signaling in
- number
- erythropoiesis
- assembly
- maturation in
- abnormal morphology
- transmigration
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- tetraspanin-enriched microdomain
- cell surface
- endoplasmic reticulum lumen
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Tspan33 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- pore complex assembly
- protein maturation
- protein localization in plasma membrane
Cellular Component
Where in the cell the gene product is active
- endoplasmic reticulum lumen
- adherens junction
- pore complex
- tetraspanin-enriched microdomain
- plasma membrane
- cell surface
Molecular Function
What the gene product does at the molecular level
- protein binding
- enzyme binding