Zfp326 Gene Summary [Rat]

Predicted to enable DNA binding activity; RNA polymerase II complex binding activity; and zinc ion binding activity. Predicted to be involved in regulation of DNA-templated transcription elongation and regulation of RNA splicing. Predicted to act upstream of or within positive regulation of DNA-templated transcription. Predicted to be located in nuclear matrix and nucleoplasm. Predicted to be part of DBIRD complex. Predicted to be active in nucleus. Orthologous to human ZNF326 (zinc finger protein 326). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Zfp326
Official Name
zinc finger protein 326 [Source:RGD Symbol;Acc:1592829]
Ensembl ID
ENSRNOG00000047761
Bio databases IDs NCBI: 682914 Ensembl: ENSRNOG00000047761
Aliases zinc finger protein 326
Synonyms 5730470H14Rik, dJ871E2.1, FLJ20403, ZAN75, Zfp326, zinc finger protein 326, ZIRD
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Zfp326 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • transcription regulator
  • zinc ion binding
  • A-kinase anchoring protein 95 (AKAP95)
  • enzyme binding
  • protein binding
  • DNA binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • neoplasia
  • systemic juvenile idiopathic arthritis
regulated by
  • Complement component 1
  • KLF4
  • fluoxetine
  • DAP3
regulates
role in cell
  • elongation in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • interchromatin granule cluster fractions
  • intracellular membrane-bounded organelle
  • nucleoplasm
  • nuclear matrix
  • chromatin
  • paraspeckle-like structures

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Zfp326 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • RNA splicing
  • regulation of RNA splicing
  • regulation of transcription elongation, DNA-dependent
  • mRNA processing

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • DBIRD complex
  • intracellular membrane-bounded organelle
  • nuclear matrix
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • DNA binding
  • RNA binding
  • protein binding
  • metal ion binding
  • RNA polymerase II core binding

Gene-Specific Assays for Results You Can Trust

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