ZNF326 Gene Summary [Human]
Enables RNA polymerase II complex binding activity. Involved in regulation of DNA-templated transcription, elongation and regulation of RNA splicing. Located in nucleoplasm. Part of DBIRD complex. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Nonsense Mediated Decay |
| Official Symbol | ZNF326 |
| Official Name | zinc finger protein 326 [Source:HGNC Symbol;Acc:HGNC:14104] |
| Ensembl ID | ENSG00000162664 |
| Bio databases IDs | |
| Aliases | zinc finger protein 326, ZNF-protein interacting with nuclear mRNPs and DBC1 |
| Synonyms | 5730470H14Rik, dJ871E2.1, FLJ20403, ZAN75, Zfp326, zinc finger protein 326, ZIRD |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human ZNF326 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- transcription regulator
- zinc ion binding
- A-kinase anchoring protein 95 (AKAP95)
- enzyme binding
- protein binding
- DNA binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- interchromatin granule cluster fractions
- intracellular membrane-bounded organelle
- nucleoplasm
- nuclear matrix
- chromatin
- paraspeckle-like structures
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human ZNF326 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- RNA splicing
- regulation of RNA splicing
- regulation of transcription elongation, DNA-dependent
- mRNA processing
Cellular Component
Where in the cell the gene product is active
- nucleus
- DBIRD complex
- intracellular membrane-bounded organelle
- nuclear matrix
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- DNA binding
- RNA binding
- protein binding
- metal ion binding
- RNA polymerase II core binding