Pcbd2 Gene Summary [Rat]
Predicted to enable 4-alpha-hydroxytetrahydrobiopterin dehydratase activity. Involved in positive regulation of transcription, DNA-templated. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | Pcbd2 |
| Official Name | pterin-4 alpha-carbinolamine dehydratase 2 [Source:RGD Symbol;Acc:1590239] |
| Ensembl ID | ENSRNOG00000047796 |
| Bio databases IDs | |
| Aliases | pterin-4 alpha-carbinolamine dehydratase 2 |
| Synonyms | 2700061N24Rik, DCOH, DCOH2, DCOHM, LOC102555972, LOC683319, PHS2, pterin-4 alpha-carbinolamine dehydratase 2, pterin 4 alpha carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2, pterin-4 α-carbinolamine dehydratase 2, pterin 4 α carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 α (TCF1) 2 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Pcbd2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- 4a-hydroxytetrahydrobiopterin dehydratase
- phenylalanine 4-monooxygenase
- PCD_DCoH
- Pterin 4 alpha carbinolamine dehydratase
- enzyme
- protein binding
- identical protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- Mitochondria
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Pcbd2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- tyrosine biosynthetic process, by oxidation of phenylalanine
- tetrahydrobiopterin biosynthetic process
- positive regulation of transcription, DNA-dependent
Cellular Component
Where in the cell the gene product is active
- nucleus
Molecular Function
What the gene product does at the molecular level
- identical protein binding
- protein binding
- phenylalanine 4-monooxygenase activity
- 4-alpha-hydroxytetrahydrobiopterin dehydratase activity