Klhdc8b

Predicted to be involved in mitotic cytokinetic process; mitotic nuclear division; and nuclear chromosome segregation. Predicted to be located in cytosol. Predicted to be active in cellularization cleavage furrow; intercellular bridge; and midbody. Human ortholog(s) of this gene implicated in Hodgkin's lymphoma. Orthologous to human KLHDC8B (kelch domain containing 8B). [provided by Alliance of Genome Resources, Jul 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Klhdc8b often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the rat Klhdc8b gene, providing context for its role in the cell.