Pex26 Gene Summary [Rat]
Predicted to enable ATPase binding activity and protein-membrane adaptor activity. Predicted to be involved in protein import into peroxisome matrix and protein to membrane docking. Predicted to be located in peroxisome. Predicted to be active in peroxisomal membrane. Human ortholog(s) of this gene implicated in Peroxisome biogenesis disorder 7B and peroxisome biogenesis disorder 7A. Orthologous to human PEX26 (peroxisomal biogenesis factor 26). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Pex26 |
| Official Name | peroxisomal biogenesis factor 26 [Source:RGD Symbol;Acc:1584998] |
| Ensembl ID | ENSRNOG00000049982 |
| Bio databases IDs | |
| Aliases | peroxisomal biogenesis factor 26 |
| Synonyms | 4632428M11RIK, PBD7A, PBD7B, peroxisomal biogenesis factor 26, PEX26M1T, Pex26p, Pex26pM1T |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Pex26 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- ATPase binding
- binding protein
- protein binding activity, bridging
- protein binding
- Pex26 protein
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- peroxisome biogenesis disorder 7a (zellweger)
- peroxisome biogenesis disorder
- peroxisome biogenesis disorder 7B
- Zellweger syndrome
- infantile refsum disease
regulates
role in cell
- biogenesis in
- biogenesis
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cytosol
- peroxisome membrane
- peroxisomes
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Pex26 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- protein import into peroxisome matrix
- protein to membrane docking
- protein import into peroxisome membrane
Cellular Component
Where in the cell the gene product is active
- peroxisomal membrane
- peroxisome
- cytosol
Molecular Function
What the gene product does at the molecular level
- protein binding
- protein anchor
- ATPase binding