Samd9 Gene Summary [Rat]
Predicted to be involved in endosomal vesicle fusion. Predicted to be located in cytosol and intracellular membrane-bounded organelle. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in normophosphatemic familial tumoral calcinosis. Orthologous to human SAMD9 (sterile alpha motif domain containing 9). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Samd9 |
| Official Name | sterile alpha motif domain containing 9 [Source:RGD Symbol;Acc:1563091] |
| Ensembl ID | ENSRNOG00000052444 |
| Bio databases IDs | |
| Aliases | sterile alpha motif domain containing 9 |
| Synonyms | C7ORF5, DRIF1, FLJ20073, M7MLS2, MIRAGE, NFTC, OEF1, OEF2, RGD1563091, sterile alpha motif domain containing 9, sterile α motif domain containing 9 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Samd9 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Sterile alpha motif
- SAM (Sterile alpha motif )
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- flu
- COVID-19
- hereditary disorder
- breast cancer
- monosomy 7 myelodysplasia and leukemia syndrome type 2
- normophosphatemic familial tumoral calcinosis
- MIRAGE syndrome
- B-cell non-Hodgkin lymphoma
- B-cell non-Hodgkin disease
- sepsis
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- intracellular membrane-bounded organelle
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Samd9 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- innate immune response
- endosomal vesicle fusion
Cellular Component
Where in the cell the gene product is active
- cytoplasm
- intracellular membrane-bounded organelle
- cytosol
Molecular Function
What the gene product does at the molecular level
- protein binding