Rpap3 Gene Summary [Rat]
Predicted to be located in ciliary basal body and cytosol. Predicted to be part of R2TP complex; RPAP3/R2TP/prefoldin-like complex; and protein folding chaperone complex. Orthologous to human RPAP3 (RNA polymerase II associated protein 3). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Rpap3 |
| Official Name | RNA polymerase II associated protein 3 [Source:RGD Symbol;Acc:1303036] |
| Ensembl ID | ENSRNOG00000053405 |
| Bio databases IDs | |
| Aliases | RNA polymerase II associated protein 3 |
| Synonyms | 2310042P20Rik, D15Ertd682e, hSpagh, MSPAGHETTI, RNA polymerase II associated protein 3, Spagh, Tah1 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Rpap3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- TPR repeat
- Tetratricopeptide repeats
- enzyme
- protein binding
- tetratricopeptide repeat
- Potential Monad-binding region of RPAP3
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cilia
- basal bodies
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Rpap3 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- protein stabilization
Cellular Component
Where in the cell the gene product is active
- R2TP complex
- cytosol
Molecular Function
What the gene product does at the molecular level
- protein binding