Snd1 Gene Summary [Rat]
Predicted to enable RISC complex binding activity; RNA binding activity; and RNA endonuclease activity. Predicted to be involved in mRNA catabolic process; miRNA catabolic process; and regulation of cell cycle process. Predicted to be located in dense body. Predicted to be part of RNAi effector complex. Predicted to be active in cytosol and nucleus. Orthologous to human SND1 (staphylococcal nuclease and tudor domain containing 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Snd1 |
| Official Name | staphylococcal nuclease and tudor domain containing 1 [Source:RGD Symbol;Acc:631340] |
| Ensembl ID | ENSRNOG00000031173 |
| Bio databases IDs | |
| Aliases | staphylococcal nuclease and tudor domain containing 1 |
| Synonyms | Loc56463, p100, P100-coactivator, SND p102, staphylococcal nuclease and tudor domain containing 1, TDRD11, TSN, Tudor-SN, U83883 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Snd1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- transcription regulator
- Tudor domain
- transcription co-activator
- Staphylococcal nuclease homologues
- transcription cofactor
- protein binding
- MYB binding EVES domain
- RNA binding
- endonuclease
- ribonucleoprotein binding
- endoribonuclease
- SNc
- Tudor domain superfamily
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- prostate cancer
- schizophrenia
- organismal death
- peptic ulcer disease
- lung metastasis
- non-insulin-dependent diabetes mellitus
- hemorrhoid
- pervasive developmental disorder
- rheumatoid arthritis
- insomnia
role in cell
- apoptosis
- growth
- activation in
- proliferation
- upregulation in
- expression in
- downregulation in
- recruitment in
- cell viability
- cell cycle progression
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- detergent resistant lipid raft fraction
- Cytoplasm
- punctate structures
- Endoplasmic Reticulum
- granules
- cytosol
- extranucleolar nucleoplasm
- perikaryon
- axons
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Snd1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- osteoblast differentiation
- gene silencing by RNA
- mRNA catabolic process
- miRNA catabolic process
- regulation of cell cycle process
Cellular Component
Where in the cell the gene product is active
- nucleus
- extracellular vesicular exosome
- melanosome
- membrane
- RNAi effector complex
- cytosol
Molecular Function
What the gene product does at the molecular level
- transcription cofactor activity
- RNA binding
- protein binding
- cadherin binding
- endonuclease activity
- nuclease activity
- endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters
- endoribonuclease activity