Tarbp1 Gene Summary [Rat]

Predicted to enable tRNA (guanine) methyltransferase activity. Predicted to be involved in tRNA methylation. Orthologous to human TARBP1 (TAR (HIV-1) RNA binding protein 1). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Tarbp1
Official Name
TAR (HIV-1) RNA binding protein 1 [Source:RGD Symbol;Acc:1589526]
Ensembl ID
ENSRNOG00000053574
Bio databases IDs NCBI: 679346 Ensembl: ENSRNOG00000053574
Aliases TAR (HIV-1) RNA binding protein 1
Synonyms Gm17296, Gm179, TAR (HIV-1) RNA binding protein 1, TAR RNA binding protein 1, TRM3, TRMT3, tRNA guanosine 2 -O-methyltransferase TARBP1, TRP-185
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Tarbp1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • transcription regulator
  • tRNA (guanine) methyltransferase
  • SPOUT superfamily of SAM-dependent RNA methyltransferases
  • RNA binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • schizophrenia
regulates
  • DNA promoter
  • DNA endogenous promoter
  • RNA polymerase II

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Tarbp1 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • tRNA methylation
  • regulation of transcription from RNA polymerase II promoter

Cellular Component

Where in the cell the gene product is active
  • nucleus

Molecular Function

What the gene product does at the molecular level
  • RNA binding
  • tRNA (guanine) methyltransferase activity

Gene-Specific Assays for Results You Can Trust

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