Tarbp1 Gene Summary [Mouse]
Predicted to enable tRNA (guanine) methyltransferase activity. Predicted to be involved in tRNA methylation. Is expressed in cerebral cortex; heart; reproductive system; and thyroid gland. Orthologous to human TARBP1 (TAR (HIV-1) RNA binding protein 1). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Tarbp1 |
| Official Name | TAR RNA binding protein 1 [Source:MGI Symbol;Acc:MGI:4936930] |
| Ensembl ID | ENSMUSG00000090290 |
| Bio databases IDs | |
| Aliases | TAR RNA binding protein 1 |
| Synonyms | Gm17296, Gm179, TAR (HIV-1) RNA binding protein 1, TAR RNA binding protein 1, TRM3, TRMT3, tRNA guanosine 2 -O-methyltransferase TARBP1, TRP-185 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Tarbp1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- transcription regulator
- tRNA (guanine) methyltransferase
- SPOUT superfamily of SAM-dependent RNA methyltransferases
- RNA binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Tarbp1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- tRNA methylation
- regulation of transcription from RNA polymerase II promoter
Cellular Component
Where in the cell the gene product is active
- nucleus
Molecular Function
What the gene product does at the molecular level
- RNA binding
- tRNA (guanine) methyltransferase activity