Tmprss11d Gene Summary [Rat]

Enables serine-type peptidase activity. Involved in regulation of growth. Located in cell surface. Orthologous to human TMPRSS11D (transmembrane serine protease 11D). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Tmprss11d
Official Name
transmembrane serine protease 11D [Source:RGD Symbol;Acc:620654]
Ensembl ID
ENSRNOG00000055991
Bio databases IDs NCBI: 64565 Ensembl: ENSRNOG00000055991
Aliases transmembrane serine protease 11D
Synonyms Adrenal secretory serine protease precursor, AF198087, ASP, AST, At, HAT, transmembrane protease, serine 11d, transmembrane serine protease 11D
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Tmprss11d often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Trypsin-like serine protease
  • trypsin
  • Tryp_SPc
  • serine-type peptidase
  • peptidase
  • SEA domain
  • Domain of unknown function (DUF1986)
  • Trypsin-like peptidase domain
  • protein binding

Pathways

Biological processes and signaling networks where the Tmprss11d gene in rat plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
regulated by
  • spermine
  • decitabine
  • aprotinin
  • heavy metal
  • genistein
  • NR5A1
  • antipain
  • soybean trypsin inhibitor
  • SERPINB7
  • leupeptin
regulates
role in cell
  • production in
  • activation in
  • molecular cleavage in
  • growth in
  • fusion
  • replication in
  • spreading in
  • entrance

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Extracellular Space
  • tetraspanin-enriched microdomain
  • cell surface
  • cellular membrane
  • Plasma Membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Tmprss11d gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • proteolysis
  • respiratory gaseous exchange

Cellular Component

Where in the cell the gene product is active
  • extracellular vesicular exosome
  • extracellular region
  • plasma membrane

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • serine-type endopeptidase activity
  • peptidase activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.