Pym1 Gene Summary [Rat]

Predicted to enable RNA binding activity and ribosome binding activity. Predicted to be involved in exon-exon junction complex disassembly; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; and positive regulation of translation. Predicted to be located in cell junction; cytosol; and nuclear lumen. Predicted to be part of exon-exon junction complex. Predicted to be active in cytoplasm. Orthologous to human PYM1 (PYM homolog 1, exon junction complex associated factor). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Pym1
Official Name
PYM homolog 1, exon junction complex associated factor [Source:RGD Symbol;Acc:1306096]
Ensembl ID
ENSRNOG00000058130
Bio databases IDs NCBI: 366790 Ensembl: ENSRNOG00000058130
Aliases PYM homolog 1, exon junction complex associated factor
Synonyms A030010B05Rik, BC006135, PYM, PYM homolog 1, exon junction complex associated factor, RGD1306096, WIBG
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Pym1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Mago binding
  • ribosome binding
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulated by
  • Core
  • Huh-7.5 cells

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • cell junction
  • cytosol
  • nucleoplasm
  • nucleoli

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Pym1 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • positive regulation of translation
  • nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

Cellular Component

Where in the cell the gene product is active
  • exon-exon junction complex
  • cytoplasm
  • cytosol
  • cell junction
  • nucleolus
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • RNA binding
  • protein binding
  • ribosome binding

Gene-Specific Assays for Results You Can Trust

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