PYM1 Gene Summary [Human]
Enables ribosome binding activity. Involved in exon-exon junction complex disassembly; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; and positive regulation of translation. Located in cell junction; cytosol; and nuclear lumen. Part of exon-exon junction complex. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | PYM1 |
| Official Name | PYM homolog 1, exon junction complex associated factor [Source:HGNC Symbol;Acc:HGNC:30258] |
| Ensembl ID | ENSG00000170473 |
| Bio databases IDs | |
| Aliases | PYM homolog 1, exon junction complex associated factor, partner of Y14 and Mago |
| Synonyms | A030010B05Rik, BC006135, PYM, PYM homolog 1, exon junction complex associated factor, RGD1306096, WIBG |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human PYM1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Mago binding
- ribosome binding
- protein binding
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- cell junction
- cytosol
- nucleoplasm
- nucleoli
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human PYM1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- positive regulation of translation
- nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
Cellular Component
Where in the cell the gene product is active
- exon-exon junction complex
- cytoplasm
- cytosol
- cell junction
- nucleolus
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- RNA binding
- protein binding
- ribosome binding