Details

Type
Protein Coding
Official Symbol
Sry
Official Name
sex determining region Y [Source:RGD Symbol;Acc:3759]
Ensembl ID
ENSRNOG00000062090
Bio databases IDs NCBI: 25221 Ensembl: ENSRNOG00000062090
Aliases sex determining region Y
Synonyms LOC103694545, sex determining region of Chr Y, sex determining region Y, Sry3B, SRYGENE, Tdf, Tdy
Species
Rat, Rattus norvegicus
OrthologiesMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Sry often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • transcription regulator
  • high mobility group (HMG)-box domain superfamily
  • enzyme binding
  • DNA bending protein
  • transcription factor binding
  • protein binding
  • glutamine-rich domain
  • sequence-specific DNA binding
  • DNA binding
  • RNA polymerase II transcription factor activity, sequence-specific DNA binding
  • HMG-like domain
  • HMG (high mobility group) box
  • HMG-box domain
  • high mobility group
  • glutamine repeat domain
  • histidine glutamine rich domain

Pathways

Biological processes and signaling networks where the Sry gene in rat plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
disease
  • neuroinflammation
  • motor dysfunction
regulated by
  • EP300
  • rotenone
  • calmidazolium
  • 6-hydroxydopamine
  • W7
  • halofuginone
  • WT1
  • SOX9
  • isoprenaline
  • CBX2
regulates
role in cell
  • expression in
  • activation in
  • growth
  • signaling in
  • proliferation
  • invasiveness
  • tumorigenicity
  • degeneration
  • degradation

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • nucleoplasm
  • chromatin

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.