GeneGlobe ID: UPHS-040Z | Cat. No.: 249955 | QuantiNova LNA Probe PCR Focus Panels

QuantiNova LNA Probe PCR Focus Panel Human EGF / PDGF Signaling Pathway

QuantiNova LNA Probe PCR Focus Panel
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Product Specification

Target List
EGFR Signaling
BCAR1, CBL, EGF, EGFR (ERBB1), EPS8, GAB1, GRB2, HBEGF, NCK2, NUP62, RPS6KA5, SHC1
Platelet-Derived Growth Factor Receptor Signaling
BCAR1, PDGFA, PDGFB, PDGFRA, PLAT (TPA)
Intracellular Signaling
AKT Signaling​
AKT1, AKT2, AKT3, BAD, CASP9, CHUK (IKKα), FASLG (TNFSF6), FOXO3, NFKB1, PTEN
ERK1 / ERK2 Signaling​
EGFR (ERBB1), ELK1, GRB2, MAP2K1, MAPK1 (ERK2), MAPK3 (ERK1), MKNK1, PDGFRA, RAF1, RPS6KA5, SHC1, SRC, STAT3
IκB Kinase / NFκB Cascade​
CHUK (IKKα), FASLG (TNFSF6), GSK3A, GSK3B, NUP62, RHOA, STAT1
JAK / STAT Signaling​
EPS8, GAB1, GRB2, JAK1, NUP62, PPP2CA, SRC, STAT1, STAT3, STAT5A
JNK / p38 Signaling​
MAP2K4 (MKK4, JNKK1), MAP3K2 (MEKK2), MAPK10 (JNK3), MAPK8 (JNK1), MAPK9 (JNK2)
MAP Kinase Signaling​
DUSP1 (PTPN16), DUSP6, EGF, EGFR (ERBB1), MAP2K1, MAP2K7 (JNKK2), MAPK1 (ERK2), MAPK10 (JNK3), MAPK3 (ERK1), MAPK8 (JNK1), MAPK9 (JNK2), PPP2CA, PRKCA, SHC1
PI3 Kinase Signaling​
PIK3CA (p110-alpha), PIK3R1 (p85-ALPHA), PIK3R2 (p85-BETA), PTEN
G-Protein Signaling​
GRB2, HRAS, NRAS, NUP62, RAP1A, RASA1, RHOA
Other Intracellular Signaling Molecules​
ARAF, BRAF, CBL, CSNK2A1, CSNK2B, IKBKB (IKKβ), NCK2, PDPK1, PLCG1, RPS6KB1
Cell Survival & Growth
Apoptosis​
AKT1, BAD, BCAR1, BCL2, BRAF, CASP3, CASP9, FASLG (TNFSF6), FOXO3, IL2, LTA (TNFB), MAPK1 (ERK2), NFKB1, NUP62, PIK3R2 (p85-BETA), PPP2CA, PRKCA, PTEN, RAF1, RASA1, STAT1, TP53 (p53)
Cell Cycle​
BCL2, CCND1, DUSP1 (PTPN16), DUSP6, EGFR (ERBB1), HRAS, KRAS, MAPK1 (ERK2), MAPK3 (ERK1), NRAS, PDGFA, PDGFB, PPP2CA, PRKCA, PTEN, RAP1A, SHC1, STAT1, TP53 (p53)
Cell Differentiation​
FOXO3, IL2, PPP2CA, TP53 (p53)
Cell Growth​
BCAR1, CCND1, EGF, HBEGF, IL2, PDGFA, PDGFB, PDGFRA, PPP2CA, RASA1, SHC1, TP53 (p53)
Cell Motility​
ACTR2, BCAR1, EGFR (ERBB1), FN1, HBEGF, MAP2K1, MAPK8 (JNK1), PTEN, STAT3
Cell Proliferation​
BCAR1, BCL2, EGF, EGFR (ERBB1), EPS8, GAB1, HBEGF, IL2, NCK2, NUP62, PDGFA, PDGFB, PDGFRA, PTEN, RAF1, SHC1, TP53 (p53)
Metabolism
DNA Metabolism​
ATF1, ATF2 (CREB2), CREB1, EGF, EGFR (ERBB1), FOS, NUP62, PPP2CA, TP53 (p53)
Lipid Metabolism​
ARAF, BRAF, PIK3R1 (p85-ALPHA), PLCG1, PPP2CA, PRKCA, PTEN, RAF1, SHC1
Protein Metabolism​
ACTR2, AKT1, AKT2, AKT3, ARAF, ATF1, ATF2 (CREB2), BRAF, CBL, CHUK (IKKα), CREB1, CSNK2A1, DUSP1 (PTPN16), DUSP6, EGFR (ERBB1), FOS, GSK3A, GSK3B, IKBKB (IKKβ), JAK1, MAP2K1, MAP2K4 (MKK4, JNKK1), MAP2K7 (JNKK2), MAP3K2 (MEKK2), MAPK1 (ERK2), MAPK10 (JNK3), MAPK3 (ERK1), MAPK8 (JNK1), MAPK9 (JNK2), MKNK1, PDGFRA, PDPK1, PPP2CA, PRKCA, PTEN, RAF1, RPS6KA5, RPS6KB1, SRC
Other Metabolism Genes​
COL1A1, EIF4E, FN1, MMP7, RASA1
Development
BRAF, COL1A1, HBEGF, PTEN, RASA1, STAT3
Stimulus Response
Response to Wounding​
BCAR1, BCL2, FN1, HBEGF, IL2, NCK2, NFKB1, PDGFB, STAT3
Response to Other Stimuli​
AKT1, CHUK (IKKα), COL1A1, DUSP1 (PTPN16), EGFR (ERBB1), FASLG (TNFSF6), FOS, KRAS, LTA (TNFB), MAP2K1, MAP2K7 (JNKK2), MAPK1 (ERK2), MAPK8 (JNK1), MAPK9 (JNK2), NFATC3, PPP2CA, RPS6KA5, STAT1, STAT5A, TP53 (p53)
Transcription Factors & Regulators
AKT1, ATF1, ATF2 (CREB2), CBL, CREB1, EGR1, EIF4E, ELK1, FOS, FOXO3, IKBKB (IKKβ), JUN, MKNK1, NFATC3, NFKB1, NUP62, PPP2CA, RPS6KA5, STAT1, STAT3, STAT5A, TP53 (p53)
Actin & Calcium Ion Homeostasis
ACTR2, BCAR1, CBL, EGF, EGFR (ERBB1), MMP7, NCK2, PDPK1, PLCG1, PRKCA, RASA1, RHOA, STAT1, STAT3, STAT5A
Gene Resource List
Array Layout for PCR Plates
File Size: 153.3 KBLanguage: English
Array Layout for Rotor-Gene Q
File Size: 153.45 KBLanguage: English

Resources

Kit Handbooks (1)
QuantiNova LNA Probe PCR Handbook
Quick-Start Protocols (1)
Certificates of Analysis (1)
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