AKAP17A Gene Summary [Human]
This locus encodes a protein kinase A anchoring protein. The encoded protein is part of the spliceosome complex and is involved in the regulation of alternate splicing in some mRNA precursors. Alternatively spliced transcript variants have been identified for this gene.[provided by RefSeq, Sep 2010]
Details
| Type | Protein Coding |
| Official Symbol | AKAP17A |
| Official Name | A-kinase anchoring protein 17A [Source:HGNC Symbol;Acc:HGNC:18783] |
| Ensembl ID | ENSG00000197976 |
| Bio databases IDs | |
| Aliases | A-kinase anchoring protein 17A |
| Synonyms | 721P, A-kinase anchoring protein 17A, CCDC133, CXYorf3, DXYS155E, PRKA17A, SFRS17A, XE7, XE7Y |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human AKAP17A often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- flagellar export protein FliJ
- RNA recognition motif (RRM) superfamily
- Arginine and glutamate-rich 1
- protein kinase A binding
- MAP7 (E-MAP-115) family
- Ezrin/radixin/moesin, alpha-helical domain
- RNA recognition motif
- protein binding
Pathways
Biological processes and signaling networks where the AKAP17A gene in human plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- cellular membrane
- cytosol
- nuclear speckles
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human AKAP17A gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- RNA splicing
- signal transduction
- regulation of RNA splicing
- regulation of transcription, DNA-dependent
- mRNA processing
- B cell activation
Cellular Component
Where in the cell the gene product is active
- nucleus
- nuclear speck
- cytosol
- spliceosomal complex
Molecular Function
What the gene product does at the molecular level
- protein binding
- RNA binding
- protein kinase A binding