Mpped2 Gene Summary [Mouse]
Predicted to enable manganese ion binding activity; phosphoric diester hydrolase activity; and purine ribonucleotide binding activity. Is expressed in axial skeleton; head mesenchyme; midbrain ventricular layer; telencephalon; and thyroid cartilage. Orthologous to human MPPED2 (metallophosphoesterase domain containing 2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Mpped2 |
| Official Name | metallophosphoesterase domain containing 2 [Source:MGI Symbol;Acc:MGI:1924265] |
| Ensembl ID | ENSMUSG00000016386 |
| Bio databases IDs | |
| Aliases | metallophosphoesterase domain containing 2 |
| Synonyms | 239FB, 2700082O15Rik, Ak012553, AV354767, AW060960, C11orf8, C11orf8h, metallophosphoesterase domain containing 2 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Mpped2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- GMP binding
- AMP binding
- enzyme
- protein binding
- metallophosphatase superfamily, metallophosphatase domain
- manganese ion binding
- phosphoric diester hydrolase
- Calcineurin-like phosphoesterase
Pathways
Biological processes and signaling networks where the Mpped2 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- migraines
- dental caries
- uterine leiomyoma
- leiomyomatosis
- refractive error
- metabolic syndrome X
- thyroid carcinoma
- epithelial thyroid cancer
- diabetic nephropathy
- postural instability
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Mpped2 gene, providing context for its role in the cell.
Molecular Function
What the gene product does at the molecular level
- protein binding
- AMP binding
- GMP binding
- manganese ion binding
- phosphoric diester hydrolase activity