Fcgbp Gene Summary [Mouse]

Located in extracellular matrix. Is expressed in genitourinary system; gut; immune system; and integumental system. Orthologous to human FCGBP (Fc gamma binding protein). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Fcgbp
Official Name
Fc fragment of IgG binding protein [Source:MGI Symbol;Acc:MGI:2444336]
Ensembl ID
ENSMUSG00000047730
Bio databases IDs NCBI: 215384 Ensembl: ENSMUSG00000047730
Aliases Fc fragment of IgG binding protein
Synonyms A430096B05RIK, Fc fragment of IgG binding protein, Fc gamma binding protein, FC(GAMMA)BP, Fc γ binding protein, FC(γ)BP, LOC100133944, LOC435957
Species
Mouse, Mus musculus
OrthologiesHuman

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Fcgbp often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • von Willebrand factor type C domain
  • Trypsin Inhibitor like cysteine rich domain
  • trypsin inhibitor-like cysteine rich domain
  • IgGFc binding protein
  • von Willebrand factor type D domain
  • protein binding
  • von Willebrand factor (vWF) type D domain
  • C8 domain

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • atopic dermatitis
  • cervical cancer
  • breast cancer
  • papillary thyroid carcinoma
  • papillary thyroid cancer
  • Hodgkin lymphoma
  • Hodgkin disease
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Extracellular Space
  • detergent resistant lipid raft fraction
  • extracellular matrix

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Fcgbp gene, providing context for its role in the cell.

Cellular Component

Where in the cell the gene product is active
  • extracellular space
  • extracellular vesicular exosome
  • extracellular matrix

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.