YBX2 Gene Summary [Human]
This gene encodes a nucleic acid binding protein which is highly expressed in germ cells. The encoded protein binds to a Y-box element in the promoters of certain genes but also binds to mRNA transcribed from these genes. Pseudogenes for this gene are located on chromosome 10 and 15. [provided by RefSeq, Feb 2012]
Details
| Type | Retained Intron |
| Official Symbol | YBX2 |
| Official Name | Y-box binding protein 2 [Source:HGNC Symbol;Acc:HGNC:17948] |
| Ensembl ID | ENSG00000006047 |
| Bio databases IDs | |
| Aliases | Y-box binding protein 2 |
| Synonyms | CONTRIN, CSDA3, DBPC, MSY2, RGD1305068, Y-box binding protein 2, Y box protein 2 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human YBX2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- S1_like
- mRNA 3' UTR binding
- lipid binding
- mRNA binding
- ribonucleoprotein binding
- chromatin binding
- translation regulator
- Cold shock protein domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- breast cancer
- azoospermia
role in cell
- apoptosis
- quantity
- number
- spermatogenesis
- abnormal morphology
- development
- translation in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Nucleus
- polysomes
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human YBX2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- oocyte development
- translational attenuation
- spermatogenesis
- regulation of gene expression
- transcription from RNA polymerase II promoter
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytoplasm
Molecular Function
What the gene product does at the molecular level
- nucleic acid binding
- DNA binding
- RNA binding