RRP15 Gene Summary [Human]
This gene encodes a protein that co-purifies with human nucleoli. A similar protein in budding yeast is a component of pre-60S ribosomal particles, and is required for the early maturation steps of the 60S subunit. [provided by RefSeq, Jul 2008]
Details
| Type | Protein Coding |
| Official Symbol | RRP15 |
| Official Name | ribosomal RNA processing 15 homolog [Source:HGNC Symbol;Acc:HGNC:24255] |
| Ensembl ID | ENSG00000067533 |
| Bio databases IDs | |
| Aliases | ribosomal RNA processing 15 homolog |
| Synonyms | 2810430M08Rik,5430437H21Rik,CGI-115,KIAA0507,RGD1306106,ribosomal RNA processing 15 homolog |
| Species | Human, Homo sapiens |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human RRP15 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Rrp15p
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- metastasis
- colorectal cancer
- organismal death
- chronic obstructive pulmonary disease
- inguinal hernia
role in cell
- apoptosis
- expression in
- proliferation
- G2/M phase
- processing in
- degradation in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nucleoli
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human RRP15 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- maturation of 5.8S rRNA
- maturation of LSU-rRNA
Cellular Component
Where in the cell the gene product is active
- preribosome, large subunit precursor