ZFP64 Gene Summary [Human]
Predicted to enable DNA binding activity and metal ion binding activity. Predicted to be involved in positive regulation of cytokine production and positive regulation of transcription by RNA polymerase II. Predicted to act upstream of or within positive regulation of mRNA splicing, via spliceosome. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | ZFP64 |
| Official Name | ZFP64 zinc finger protein [Source:HGNC Symbol;Acc:HGNC:15940] |
| Ensembl ID | ENSG00000020256 |
| Bio databases IDs | |
| Aliases | ZFP64 zinc finger protein |
| Synonyms | CFP64, Gm38422, ZFP64 zinc finger protein, zinc finger protein 64, ZNF338 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human ZFP64 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Zinc finger, C2H2 type
- zinc finger
- transcription regulator
- C2H2-type zinc-finger domain
- Zinc-finger double domain
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- venous thromboembolism
- amyotrophic lateral sclerosis
- metabolic syndrome X
- organismal death
- specific language impairment
- testicular germ cell tumor
- germ cell neoplasia
regulated by
- trichostatin A
- SP2509
- tazemetostat
- decitabine
regulates
- NFkB (complex)
role in cell
- activation in
- differentiation
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- Cytoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human ZFP64 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- mesenchymal cell differentiation
- positive regulation of transcription from RNA polymerase II promoter
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytoplasm
- megasporocyte nucleus
Molecular Function
What the gene product does at the molecular level
- DNA binding
- protein binding
- metal ion binding