LSG1 Gene Summary [Human]
This gene encodes a protein related to the yeast large subunit GTPase 1. The encoded protein is necessary for cell viability and may localize in the endoplasmic reticulum, nucleus and cytoplasm.[provided by RefSeq, Feb 2009]
Details
| Type | Protein Coding |
| Official Symbol | LSG1 |
| Official Name | large 60S subunit nuclear export GTPase 1 [Source:HGNC Symbol;Acc:HGNC:25652] |
| Ensembl ID | ENSG00000041802 |
| Bio databases IDs | |
| Aliases | large 60S subunit nuclear export GTPase 1 |
| Synonyms | 5830465I20, D16Bwg1547e, large 60S subunit nuclear export GTPase 1, LOC103693591, RGD1309089 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human LSG1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- GTP binding
- ribosome biogenesis GTP-binding protein YlqF
- GTPase
- enzyme
- Circularly permuted YlqF-related GTPases
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Endoplasmic Reticulum
- cytosol
- nucleoplasm
- nuclear bodies
- Cajal bodies
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human LSG1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- ribosomal subunit export from nucleus
- nuclear export
- protein transport
Cellular Component
Where in the cell the gene product is active
- nuclear body
- membrane
- Cajal body
- cytosol
- endoplasmic reticulum
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- GTP binding
- GTPase activity