PLEKHH1 Gene Summary [Human]

Predicted to be located in cytoskeleton. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
PLEKHH1
Official Name
pleckstrin homology, MyTH4 and FERM domain containing H1 [Source:HGNC Symbol;Acc:HGNC:17733]
Ensembl ID
ENSG00000054690
Bio databases IDs NCBI: 57475 Ensembl: ENSG00000054690
Aliases pleckstrin homology, MyTH4 and FERM domain containing H1
Synonyms D630024D12RIK, KIAA1200, mKIAA1200, pleckstrin homology domain containing, family H (with MyTH4 domain) member 1, pleckstrin homology, MyTH4 and FERM domain containing H1
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human PLEKHH1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • FERM central domain
  • Band 4.1 homologues
  • flagellar export protein FliJ
  • Ezrin/radixin/moesin, alpha-helical domain
  • Ubl1_cv_Nsp3_N-like
  • Coiled-coiled domain of autophagy-related 16 (Atg16) family proteins
  • PH domain
  • Pleckstrin homology-like domain
  • FERM domain B-lobe
  • FlgN protein
  • MyTH4 domain
  • Domain of unknown function (DUF4200)

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human PLEKHH1 gene, providing context for its role in the cell.

Cellular Component

Where in the cell the gene product is active
  • cytoskeleton

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.