TIMM21 Gene Summary [Human]
Involved in mitochondrial cytochrome c oxidase assembly; mitochondrial respiratory chain complex I assembly; and protein import into mitochondrial matrix. Part of TIM23 mitochondrial import inner membrane translocase complex. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | TIMM21 |
| Official Name | translocase of inner mitochondrial membrane 21 [Source:HGNC Symbol;Acc:HGNC:25010] |
| Ensembl ID | ENSG00000075336 |
| Bio databases IDs | |
| Aliases | translocase of inner mitochondrial membrane 21 |
| Synonyms | 1700034H14Rik, 2700002I20Rik, C18orf55, HSPC154, RGD1307279, TIM21, translocase of inner mitochondrial membrane 21 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human TIMM21 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Cytochrome oxidase complex assembly protein 1
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cellular membrane
- Mitochondria
- mitochondrial intermembrane space
- mitochondrial inner membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human TIMM21 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- mitochondrial respiratory chain complex IV assembly
- protein import into mitochondrial matrix
- mitochondrial respiratory chain complex I assembly
- intracellular protein transport
Cellular Component
Where in the cell the gene product is active
- mitochondrial inner membrane presequence translocase complex
- mitochondrial inner membrane
Molecular Function
What the gene product does at the molecular level
- protein binding